Skin & Laser

Kleresca ®

This innovative biophotonic system can be used to treat acne and rosacea, and to encourage the growth of new collagen.

Kleresca® is a unique, biophotonic skin treatment system.

A multi-wavelength LED light is combined with a photoconverter gel. The gel allows the spectrum of wavelengths to penetrate deeply into the skin, enhancing the effects of the light on its own. Clinical studies of Kleresca show that treatment leads to a reduction in certain (unhelpful) skin bacteria, regulation of the immune systems within the skin and stimulation your skin’s own repair systems. 


face / neck / chest / back


usually visible after 2nd treatment & continue to improve for 3 months


from $350

The Kleresca® system consists of 3 unique photoconverter gels that are used for different skin conditions:

Kleresca® Acne is the original gel – it has been proven to significantly and safely improves acne, without discomfort or downtime.

This acne treatment is safe, non-invasive and is clinically proven to improve even severe acne, primarily by reducing inflammation in the skin. Kleresca® is ideal for patients who do not wish to undertake other acne treatment options such as prescription medication, or for those who would like to use it in addition to traditional treatments. Kleresca® is suitable for all grades of acne from mild through to severe cystic varieties.

Your Kleresca® treatment will be overseen at all times by one of our doctors. For our acne patients, we offer Kleresca® as part of a holistic, personalised treatment plan, which will often include skincare, dietary advice and oral medications where appropriate. We understand how acne can have a massive impact, and will work with you on your treatment journey to maximise results in the minimal possible time. You can read more about our approach to acne here. (link to acne page)

Who is Kleresca® Acne for?

Kleresca® is an efficient treatment for all kinds of acne vulgaris, even severe cases. Results in clinical trials have been comparable to those seen with strong prescription medication and so Kleresca® is ideal for people wishing to avoid long-term or harsh medication options. Kleresca® can be used to treat acne on the face, back and/or chest areas. To start the treatment, you should schedule an consultation in our multidisciplinary ACNE CLINIC, when you will be seen by one of our Dermal Therapists, as well as one of our Doctors if necessary, who will discuss all the appropriate options with you and determine whether Kleresca® acne treatment is right for you.

How many treatments will I need or my acne?

Kleresca® is not a once-off treatment. To be effective it requires a number of sessions over 3-6 weeks, depending upon the type and severity of your acne. We always try and schedule sessions around your school or work commitments to minimise disruption.

When can I expect to improvement in my acne?

You should see noticeable improvements to your skin as the deeper layers respond and skin repairing occurs during the six-week treatment course. For at least six weeks after your treatment, you can expect to see additional improvements to your complexion. Results have been seen to have a long-lasting effect for at least six months.

Will I need repeated courses?

Of course, it is impossible to predict the natural course of each individual patient’s acne. There are many factors, including genetic and hormonal, involved in the development and exacerbations of acne. So for some patients, only one course is needed, but for other patients it may be necessary to have intermittent top-up treatments. In some cases, a full course is needed on an annual basis.

Kleresca® Rosacea Treatment is designed to help people with rosacea and sensitive skin, by stimulating the skin’s own repair mechanisms to target the signs and symptoms of some forms of rosacea.

Feel the change

Rosacea Treatment:

  • reduces inflammation, reducing the presence of pimples, papules and pustules.
  • reduces redness and blushing by improving microvascularization.
  • reduces the overall stress level of the skin, reducing the feeling of burning and stinging.
  • induces a healing response, improving the overall skin quality.

What is Rosacea?

Rosacea is a chronic inflammatory skin condition that affects primarily the central areas of the face (cheeks, chin, nose and central forehead). It is characterised by redness, easy flushing, sensitive skin, pimples and fine red vascular lines (telangectasia). Depending upon the subtype of rosacea, it can also be expressed as enlargement of the skin of the nose (rhinophyma), or can affect the eyes, causing dryness, itchiness, and swollen red eyelids.

  • Rosacea Subtype 1 = Telangectatic: Flushing, persistent redness, vascular lines.
  • Rosacea Subtype 2 = Papulopustular: Persistent redness, swelling, bumps and pimples, burning sensation in the skin.
  • Rosacea Subtype 3 = Rhinophymal: Thickening of the skin and enlargement, usually in the nose area.
  • Rosacea Subtype 4 = Ocular: Eye irritation, burning sensation, red eyelids.

It is possible to have a combination of different subtypes of Rosacea.

What is it like living with rosacea?

Patients affected by rosacea can experience negative effects on their self esteem and self confidence. It can also affect the normal daily life of sufferers. The symptoms can appear as a response to certain triggers such as UV light, anxiety/stress, certain foods, alcohol, wind etc. Identifying and avoiding triggers can go some way towards keeping the symptoms under control.
A number of different prescription gels and creams are available in Australia to help reduce the symptoms of rosacea subtypes 1 & 2, while certain eyedrops can be useful for subtype 4. Low doses of specific oral antibiotics are sometimes used to regain control of the skin during a flare-up.

It is important to realise that rosacea is a usually a chronic skin condition and treatment is aimed at long term management and reduction of flare-ups. Early diagnosis and management can prevent symptoms progressing from mild to moderate to severe.

Kleresca® Rosacea was designed specifically to improve inflammation but also to modulate the immune function of the skin, leading to lasting results and potentially fewer flare-ups.

How Many Rosacea treatments will I need?

A course of Kleresca® Rosacea treatment is tailored for each patient, and will typically consist of either 4, 6 or 8 initial treatments spread over 3-4 weeks. Additional single treatments are then used to halt flare-ups as and when needed.

Are the results of Kleresca® Rosacea permanent?

No, unfortunately the results seen with Kleresca® Rosacea are unlikely to be permanent for most patients, due to the chronic relapsing nature of rosacea. However, since the overall immune health of the skin is improved, flare-ups would tend to be fewer and less severe. Following your initial course of Kleresca®, flare-ups can be managed with a single “rescue” treatment as and when needed.

The innovation of the Kleresca® SKR technology lies in its ability to create fluorescent light energy that activates your skin’s collagen-producing cells.

Kleresca®-SKin Rejuvenation (SKR) is the newest Kleresca® gel.

The fluorescent light energy penetrates the skin and reaches into multiple layers, boosting collagen production by stimulating the natural processes of the skin. Studies show Kleresca® SKR induces an approximate 400% increase in collagen production*.

The treatment improves your complexion by:

  • Inducing collagen production
  • Reducing pore size
  • Eliminating fine linesReducing signs of scars

Combined, these enhancements add up to an overall improvement in skin quality that patients typically describe as a feeling of radiance. Furthermore, Kleresca® SKR has been shown to continue improving the skin quality even after the course of treatments has been completed.

Kleresca® SKR was originally designed as a facial treatment but can also be used on the neck, décolletage and hands. It can be used as a stand-alone course of treatment, or in conjunction with other treatments such as DOT laser or the Hydrafacial®

How many treatments will I need?

Kleresca® SKR is a course of 4 treatments, delivered once a week for 4 consecutive weeks. Each treatment involves only a 30minute visit to the clinic, so can easily be performed in a lunch break.

Is there any downtime?

This is a gentle, non-invasive treatment with no risk of bruising. Some patients experience a temporary slight bronzing to the skin of the treated areas immediately after the treatment, and there may also be some temporary redness or mild swelling.

*With LED light as a control, the treatment delivers approximately a 400% increase in collagen production. These results were documented in-vitro and support findings from in vivo studies based on biopsies.

Tap into our medical expertise

We understand that the world of aesthetics and cosmetic treatments can be intimidating, that’s why our cosmetic doctors and qualified dermal therapists are here.

To share our medical knowledge.
To help you look and feel your best.

image of lady with kleresca gel on her back being treated for acne

How does Kleresca® work?

The process of photobiomodulation is based on evidence that photons are able to interact with the biological systems, cells and tissues, which consequently induce molecular pathways, modulating several aspects of cell biology. The clinical and biological effect of photobiomodulation is believed to originate from multiple cellular pathways, where individual wavelengths have been seen to trigger intra-cellular biochemical reactions. This often depends upon the state of the skin, where documented effects include:

  • Anti-inflammatory response, especially beneficial for conditions such as acne, rosacea and keratosis pilaris.
  • Increased normalised cell growth for wound healing
  • Photorejuvenation
  • Scar prevention and recovery.

Kleresca® treatment acts on the epidermis and the dermis of the skin. As the blue light with an optimised peak wavelength and fluency interacts with the Kleresca® photo converter gel, it is converted into a different set of fluorescent visible wavelengths in addition to the blue light emitted by the source. The photo converter gel creates hyper pulsed, multi-wavelength fluorescent light. This shift from shorter blue wavelengths to longer wavelengths within the blue, green, yellow, orange and red spectrum (400nm to 650nm) is caused by a phenomenon called Stoke’s shift. These wavelengths have the capacity to penetrate to various depths of the skin and to stimulate different tissues and cells within the skin5, Studies with the Kleresca biophotonic system in clinical trials have shown a significant reduction in inflammation in patients with moderate to severe acne6, longevity of results up to at least 6 months7, and increased collagen production with reduction in visible wrinkles8.

FAQ’s about Kleresca® treatments

Sanclemente, G et al. A prospective split-face double blind randomised placebo controlled trial to assess the efficacy of methyl aminolevulinate + red light in patients with facial photodamage. J. Eur. Acad. Dermatology Venereol. 25, 49-58 (2011) Freitas, L. F. de & Hamblin, M.R. Proposed mechanisms of photobiomodulation or low level light therapy. IEEE J See Top Quantum Electron 22 (2016) Barolet, D et al. Regulation of skin collagen metabolism in vitro using a pulsed 660nm LED light source: clinical correlation wit a single blinded study. J. Invest. Dermatol. 129, 2751-9 (2009)
Barolet, D. Light emitting diodes (LEDs) in dermatology. Semin. Cutan. Med. Surg. 27, 227-238 (2008)
Nielsen, M. E., Devemy, E., Jaworska, J. & Scapagnini, G. Introducing: photbiomodulation by low energy chromophore-induced fluorescent light. Mechanisms of Photobiomodulation Therapy. in IV, SPIE Photonics West BIOS, San Francisco 28Jan-2Feb (2017)
Antonious, C. et al. A multicentre, randomised, split-face clinical trial evaluating the efficacy and safety of chromophore gel-assisted blue light phototherapy for the treatment of acne. Int. J. Dermatol. 55, 1321-1328 (2016)
Nikolis, A. An extension of a multicentre, randomised, split-face clinical trial evaluating the efficacy and safety of chromophore gel-assisted blue light phototherapy for the treatment of acne. Int. J. Dermatol. (2017)
Nikolis, A. et al A randomised, placebo-controlled, single-blinded, split-face clinical trial evaluating the efficacy and safety of KLOX-001 gel formulation in KLOX light-emitting diode light on facial rejuvenation. Chin. Cosmet. Invest. Dermatol. 9, 115-125 (2016)